IMC Genomics
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Reproductive & Prenatal

A safer answer,
earlier in pregnancy

Our Non-Invasive Prenatal Test screens for the most common chromosomal conditions from a single maternal blood draw — as early as week 9. No risk to the pregnancy. Results in 7 to 10 days.

>99%
T21 sensitivity
9w+
Gestation from
7–10d
Turnaround
Streck cell-free DNA collection tube with plasma, buffy coat and red cell layersAnnotated 10 mL lavender-cap cfDNA tube showing plasma fraction with maternal and fetal cell-free DNA fragments, buffy coat interface, and red blood cell sediment, with clinical callouts for fetal fraction, fragment size and EDTA preservative.cfDNA · K2EDTA10 mL84Maternal plasmacfDNA · 150–200 bpfetal fraction ≥ 4%Buffy coatleukocytes · plateletsdiscardedStreck-style capstabilises cfDNA · 7 d RT10 mL whole bloodsingle peripheral drawRed blood cellscentrifuged · removedcffDNA in supernatantmaternal cfDNAfetal cfDNA (placental)plasma fraction
ISO 15189
Illumina NGS
GenQA Validated
When during pregnancy

The earliest screen available

NIPT can be drawn from the start of week 9 — earlier than any other prenatal screening test. The window stays open well into the second trimester, giving you flexibility for follow-up if needed.

Gestational timeline for NIPT eligibility with fetal fraction curvePregnancy timeline from LMP through week 22 marking dating scan, earliest NIPT draw at week 9, optimal NIPT window 9–22 weeks, NT scan at 11–14 weeks and anatomy scan at 18–22 weeks, with fetal fraction curve rising from approximately 4 percent at week 10 to approximately 12 percent by week 20.0%4%8%12%15%FETAL FRACTION≥ 4% threshold5%7%10%12%FETAL FRACTION (cffDNA / total cfDNA)OPTIMAL NIPT WINDOW · 9w 0d → 22w 0dw6w8w10w12w14w16w18w20w22LMPDating scanNT scan · 11–14wAnatomy scan · 18–22wEARLIEST DRAWw9 · cffDNA approaches 4%Most commonTwin pregnancyapplicable from w11+LATE CUTOFFregional · screening capT21 sens >99% · T18 >97% · T13 >87% · FPR < 0.1%FIRST TRIMESTER (≤ 13w 6d)SECOND TRIMESTER (14w +)key milestonedraw window node
What we screen for

Conditions covered

The IMC NIPT covers the three most common autosomal trisomies, sex chromosome aneuploidies, and — when requested — fetal sex.

T21

Down syndrome

Trisomy 21. Detection rate >99% with a false-positive rate below 0.1%.

T18

Edwards syndrome

Trisomy 18. High sensitivity in singleton pregnancies.

T13

Patau syndrome

Trisomy 13. Reported alongside the major trisomies.

SCA

Sex chromosome aneuploidies

Includes 45,X (Turner), 47,XXY (Klinefelter), 47,XXX, and 47,XYY.

XY

Fetal sex (optional)

Requested separately. Reported only at the parents' written request.

How it works

From draw to report

1

Blood draw

10 mL maternal whole blood in EDTA tubes from week 9 onward.

2

Plasma isolation

Plasma is separated; cell-free fetal DNA is extracted.

3

Sequencing

Low-coverage whole-genome sequencing on the Illumina platform.

4

Analysis

Z-score-based aneuploidy detection with internal QC.

5

Report & counseling

Result reviewed with a board-certified counselor.

Safety

Common questions

NIPT is a screening test, not a diagnostic test. Positive findings are confirmed by amniocentesis or CVS.

When can I take the NIPT test?

NIPT can be performed from as early as 10 weeks of pregnancy. It requires only a simple blood draw from the mother — no special preparation or fasting is needed.

Is NIPT safe for my baby?

Absolutely. NIPT is completely non-invasive. It analyzes fragments of your baby's DNA that naturally circulate in your blood — no needles or instruments come anywhere near the baby. There is zero risk of miscarriage.

What conditions does NIPT screen for?

NIPT screens for the most common chromosomal conditions: Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), Patau syndrome (Trisomy 13), and sex chromosome abnormalities including Turner syndrome and Klinefelter syndrome. Fetal sex can also be determined if desired.

How is NIPT different from the standard prenatal blood tests?

Traditional first-trimester screening (combined test) has a detection rate of about 85-90% for Down syndrome with a 5% false positive rate. NIPT has a detection rate over 99% with a false positive rate below 0.1%, meaning far fewer unnecessary invasive procedures.

What happens if I get a high-risk result?

A high-risk NIPT result does not mean your baby definitely has the condition — it means the risk is elevated and diagnostic testing (amniocentesis or CVS) is recommended to confirm. We offer genetic counseling to help you understand your results and next steps.

Discuss NIPT with your provider

Whether you are a patient asking about prenatal screening or a provider ordering for a patient, our team can answer your clinical and logistical questions.