IMC Genomics
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Preventive & Predictive

The right drug,
at the right dose,
first time

Our PGx panel genotypes 30+ pharmacogenes — including CYP2D6, CYP2C19, VKORC1, SLCO1B1, and DPYD — to predict response to 100+ commonly prescribed medications. CPIC- and DPWG-aligned recommendations come with every report.

30+
Pharmacogenes
100+
Medications
CPIC
Aligned
Two-tone pharmacogenomic capsule with emerging DNA helix and metabolizer legendA bicolored pharmaceutical capsule, half teal and half navy, intersected by a stylized double helix that emerges from the seam, annotated with CPIC Level A label, CYP2D6 reduced-function star-4 allele callout, and a five-tier metabolizer phenotype legend from poor to ultrarapid.CPIC-APGxCYP2D6 *4 / *4c.1846G>A · spliceno function · PMCYP2C19 *17increased · RMCPIC LEVEL AMETABOLIZER PHENOTYPEPMIMNMRMUM
CPIC-aligned
DPWG-aligned
Lifetime profile
Who benefits

Built for everyday prescribing decisions

Pharmacogenomic results are most useful when generated before the first prescription that needs them — and they remain valid for life.

Polypharmacy patients

Anyone on three or more chronic medications, where interactions and metabolism stack up.

Mental-health prescribing

SSRIs, SNRIs, and tricyclics route through CYP2D6 and CYP2C19. Knowing metabolizer status shortens trial-and-error cycles.

Cardiovascular care

Clopidogrel, warfarin, and statins all have well-established pharmacogenomic guidance.

Pre-surgical & oncology

DPYD before fluoropyrimidines, TPMT before thiopurines, UGT1A1 before irinotecan — high-risk drug-gene pairs.

Drug-gene interaction matrix

How a result reads on this panel

Below is an illustrative example of the matrix layout we use in patient and provider reports. Real reports are individualized to the genotyped sample.

Class · MedicationCYP2C19CYP2D6CYP2C9VKORC1SLCO1B1TPMTDPYDHLA-BCPIC
ClopidogrelantiplateletPMA
WarfarinanticoagulantIMIMA
Codeineopioid analgesicNMA
Tramadolopioid analgesicIMA
FluoxetineSSRI · antidepressantNMPMA
SertralineSSRI · antidepressantNMA
ParoxetineSSRI · antidepressantPMA
AmitriptylineTCA · antidepressantNMIMA
Simvastatinstatin · lipidPMA
AtomoxetineADHD · NRIPMA
OmeprazolePPIIMB
VoriconazoleantifungalPMA
Abacavirantiretroviral*57:01A
Carbamazepineantiepileptic*15:02A
Allopurinolurate-lowering*58:01A
AzathioprineimmunosuppressantNMA
5-FluorouracilchemotherapyIMA
NM Normal metabolizer — standard dose
IM Intermediate — caution / dose review
PM Poor metabolizer / risk allele — alternative agent
Not applicable
A CPIC Level A — actionable
B Level B — consider
Hover a row in your patient report for full CPIC guidance
Metabolizer types

Four phenotypes, plain language

For most pharmacogenes, your two inherited alleles combine into one of four metabolizer phenotypes that drive dosing recommendations.

UM

Ultrarapid

Drug is broken down faster than expected. Standard doses may be ineffective; alternative therapy may be needed.

NM

Normal

Drug metabolism is in the typical range. Standard dosing applies.

IM

Intermediate

Reduced enzyme activity. Dose adjustment or alternate agent may be considered.

PM

Poor

Little or no enzyme activity. Standard doses can be ineffective or toxic — alternative therapy is often warranted.

In practice

Prescriber workflow

Once a patient is genotyped, results integrate cleanly into how a prescription is actually written.

01 — ORDER

Saliva or blood

Sample is collected once and never needs to be repeated.

02 — RESULT

Lifetime PGx profile

Star-allele calls and metabolizer status across 30+ pharmacogenes.

03 — PRESCRIBE

CPIC-aligned guidance

For every relevant drug, the report cites CPIC and DPWG dosing recommendations.

04 — REUSE

Future prescriptions

Profile is referenced for every future drug decision over the patient's lifetime.

Bring PGx into your prescribing

Whether you are starting a new medication or routinely optimizing chronic therapy, our PGx team can review your case and route the right report to your provider.